Evolution of the Total Synthesis of (−)-Okilactomycin Exploiting a Tandem Oxy-Cope Rearrangement/Oxidation, a Petasis−Ferrier Union/Rearrangement, and Ring-Closing Metathesis
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چکیده
منابع مشابه
Tandem Ring-Opening-Ring-Closing Metathesis for Functional Metathesis Catalysts.
Use of a tandem ring-opening-ring-closing metathesis (RORCM) strategy for the synthesis of functional metathesis catalysts is reported. Ring opening of 7-substituted norbornenes and subsequent ring-closing metathesis forming a thermodynamically stable 6-membered ring lead to a very efficient synthesis of new catalysts from commercially available Grubbs' catalysts. Hydroxy functionalized Grubbs'...
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A stereoselective synthesis of (+)-physoperuvine, a tropane alkaloid from Physalis peruviana Linne has been developed using a one-pot tandem aza-Claisen rearrangement and ring closing metathesis reaction to form the key amino-substituted cycloheptene ring.
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A novel synthetic route to spirocyclic thiazolidinediones is reported by utilizing ring-closing metathesis (RCM). A selective cross metathesis (CM) of N-allyl azaspiro derivatives with different olefins has been demonstrated to prepare substituted azaspiro-[4.4]nonenediones. The X-ray crystal structure of a spirocyclic thiazolidinedione dimer is described, which has been prepared in two steps f...
متن کاملthe investigation of the relationship between type a and type b personalities and quality of translation
چکیده ندارد.
Ring-closing metathesis for the synthesis of a molecular gyrotop.
Macrocage molecules with a bridged phenylene rotor have been synthesized as molecular gyrotops, whose cages were constructed by ring-closing metathesis (RCM) of bis(trialkenylsilyl)benzenes. An analysis of the yields of the products in the RCM reaction under various temperature conditions revealed that the desired cage, i.e., a molecular gyrotop, was produced in good yield under reflux, indicat...
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ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 2009
ISSN: 0002-7863,1520-5126
DOI: 10.1021/ja8084669